Will and Isaac Baker are brothers, aged 6 and 3, from Colchester, Essex. Their grandparents are active members of The Ark Methodist Church, and Will and Isaac's parents regularly bring Will and Isaac to Sunday School at The Ark. Both boys have a particular strain of Duchenne Muscular Dystrophy. PTC Therapeutics, based in the USA, have developed a drug - Translarna - which is the first drug ever to be developed specifically to treat the strain of Duchenne Muscular Dystrophy which both Will and Isaac have. The drug has been approved in the European Union and in a small number of countries across the world. The drug has also been approved for a 6 month period for a boy in Scotland only last week. It is critical that NHS England approve this drug while the boys still have mobility and meet the prescribing criteria. Will, who is now 5 (his 6th birthday is next week), meets all the criteria to commence treatment immediately. Isaac is 3 yrs 7mths and hopefully will do so on his 5th birthday.

The commitment to purchase electricity from a future Hinckley C is eye-wateringly expensive. By contrast, the cost now for continuing our support for renewable energy is a tiny fraction of that amount. Britain's national interest is being sacrificed on the altar of Chinese-invested-and-profited but UK-taxpayer-funded nuclear power. We should take the opportunity to invest in renewable energy now, while borrowing costs are low.

The proposals in the Bill are designed to negate the ability of trade unions to effectively represent their members and hamper their support for political campaigns which can be used to defend vulnerable groups in our society. The Bill acts in contradiction to individual rights, fairness and social justice and therefore must be opposed.

* Steel is a strategic material. Without it we cannot exist on our own, supply our own industries, fight a war if the worst occurred. * Skilled jobs are being lost, these skills may not come back and our industrial future is in peril * Families are suffering, far better to assist the companies in the short term than pay dole to the redundant workers. * Britain needs to look to the long term industrial future like Germany and support its industries.

Recent studies in Sweden have shown that a 6 hour working day is optimal in terms of productivity and physical and mental health.

David Cameron announced we’ll welcome 20,000 more Syrian refugees. But there’s a catch. This will take 5 years, leaving thousands of refugees in limbo. It’s now up to us to show that in cities, towns and villages all across the country we’re ready to welcome people now. Aylan, the toddler who drowned fleeing Syria, was just three years old. His town was under attack by Isis. His five year old brother and his mum also died trying to reach safety.We don't want Britain to be the kind of country that turns its back as people drown in their desperation to flee places like Syria. So let's stand up for Britain's long tradition of helping refugees fleeing war. Let's show the Prime Minister that we, the people of the UK, are proud to do our part and provide refuge to people in their hour of need. Please sign and share, or start your own petition for your town or city here: https://you.38degrees.org.uk/efforts/refugees-welcome

There is no need for the risk! If you're going to drink, have somebody else drive. In 2013, 260 people were killed and 1,100 were seriously injured as a result of drink driving. More than 70,000 people every year are caught drink driving. If you fail a roadside breath test and are found guilty of drink driving, you may get: six months in prison, an unlimited fine, a driving ban for at least 12 months, a criminal record. Effects of alcohol on driving: Any amount of alcohol affects your judgement and your ability to drive safely. You may not notice the effects but even a small amount of alcohol can: reduce your co-ordination, slow down your reactions, affect your vision, affect how you judge speed and distance, make you drowsy. Alcohol can also make you more likely to take risks, which can create dangerous situations for you and other people. How long do the effects last? Alcohol takes time to leave your body. For example: if you drink at lunchtime, you may be unfit to drive in the evening, if you drink in the evening, you may be unfit to drive the next morning.

It has never been clear since the dawn of the digital downloads era and we, the artists, often earn a very little income from selling a good amount of our music works which cost us a lot of time, love and money. It is important because the music industry is in crisis because of greedy companies like these (Deezer and others). Whilst I am a full time working musician, working hard and struggling to survive, these people and their employees which little have to do with music, make 20 times our profit just by addressing the products WE create, somewhere. ITunes for instance has a much fairer share of the profits with the artists who sell on it. I am a music producer, band leader of a successful Funk band, having sold 1715 copies of my first album on spotify and having earned 5.4€ from it sounds rather offensive. This is not the way the music business should go as they are killing the arts and the art of recording albums. I shall make my money back from the works I sell, not funding my music through borrowed money. We demand a fairer share of these streamed music deals, because in the past they've promised that they would give us more when they'd have more subscribers. Spotify accounts for 20 million active users and still pays artists around 0.002 pence per stream. This has to come to an end!

He has brought the sport of rugby into disrepute with his disrespectful behaviour following the Scotland v Australia quater final match at the 2015 Rugby World Cup.

Southwark Council has a new policy about tree planting: that no trees are to be planted on pavements less than 2.1m wide, excluding the kerb. That is, as you'll see if you take your tape measure outside, a pretty wide pavement; most of our residential streets are narrower. Many of those streets already have trees on them. These trees are beloved parts of the neighbourhood: they freshen the environment, add beauty through the seasons, and make London feel a better place for people to live and thrive. The trouble is, Southwark's policy means that if any of these much-loved trees get damaged, vandalised or diseased, the Council is now simply cutting them down, rooting them out and paving over where they used to be, leaving behind a sadder, duller street. It's one thing to say that you won't plant new trees - though many of us would be happy to see more trees even in narrow streets - but quite another to say you won't replace old ones that were seen as a popular adornment, not a nuisance, by the people who actually lived in the area. We love these trees, and when they die, we mourn them. Refusing to replace them doesn't make the neighbourhoods more convenient: it impoverishes them, and probably decreases the value of our property as well. Southwark Council, we are asking you to do the right thing for people and for nature and change your policy so that trees that meet with misfortunes can be replaced even if they were growing in the smaller streets. We, the people who live in these streets, want the trees. Please hear us.

Tax credits are used to boost the wages of low income workers and act as a vital lifeline for many working families struggling to make ends meet. My daughter is a junior doctor with a two year-old and a disabled partner. Child care is so expensive, so she has to work part time, and rent is so high, so her family rely on tax credits. It's absurd that a young junior doctor and her family should face poverty because of the withdrawal of tax credits. And that's exactly what's happening under the current government. My daughter’s family is beleaguered on all fronts. This is the kind of hard-working family that the Tories talk about and the kind that society wants. So why the punishment? It's going to mean that they can't buy shoes for their two-year old, or food, it's as bad as that. I can see a scenario where they'll be going to their local food bank, and that just doesn't make sense, that you can work so hard and be faced with going to a food bank. I wonder how the public would feel if the doctor treating them for a heart attack had been queuing for a food bank earlier that day? She's doing life-saving work with all the extra stress of poverty.

David Cameron pledged before the election that tax credits were "not going to fall". However, George Osborne's welfare reforms have included tax credit cuts that effectively act as a work penalty; punishing hard-working lower-income families. Both the Treasury select committee and the Work and Pensions select committee have requested a full impact assessment from the Government, yet Cameron and Osborne have attempted to brush the effects of their cuts under the carpet by only setting out the impact on income for families already in receipt of tax credits. We need analysis of the impact on income that the tax credit cuts will have on the population as a whole, not just those already in receipt of tax credits, so that we can see the true, devastating effects of these welfare reforms.